If disturbed, they often strike repeatedly at the intruder while vibrating their tail. In dry leaves, the vibrating of the tail may resemble the buzz of a rattlesnake fooling some predators in to leaving them alone. Large numbers are bred annually ensuring that there is a large captive-bred population, lifting the need to collect specimens from the wild.

Due to their reddish-orange coloration, Corn Snakes are often killed because they are mistaken for the copperhead, a venomous species.

Although their colour may make you think otherwise, they do not have fangs and are not venomous, they kill their prey by constriction.

After many generations of selective breeding, domesticated corn snakes are found in a wide variety of different colours and patterns.